HSS105499

• Gene Symbol: IRF1
• Gene Name: interferon regulatory factor 1
• Gene Aliases: IRF-1, MAR
• Chromosome Location: Chr.5: 132481609 - 132490789 on Build GRCh38
• UniGene ID: Hs.436061
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IRF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002198.2	NP_002189.1	2	272
	XM_011543378.2	XP_011541680.1	2	272
GenBank mRNA	AB103081.1	-	1	38
	AK314025.1	-	2	272
	BC009483.2	-	2	241	3623414
	BT019755.1	-	1	38
	BT019756.1	-	1	38
	CR541713.1	-	1	38
	KC209827.1	-	2	154
	KC209828.1	-	2	154
	KJ200632.1	-	2	154
	KJ200633.1	-	2	154
	KJ200634.1	-	2	154
	X14454.1	-	2	235

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012591, BC076382, M34253.
This siRNA also targets the following transcripts in Mouse: NM_001159393, NM_001159396, NM_008390, M21065, AK157347, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

regulation of adaptive immune response
transcription from RNA polymerase II promoter
apoptotic process
cell cycle arrest
blood coagulation
negative regulation of cell proliferation
positive regulation of type I interferon production
positive regulation of interferon-beta production
regulation of MyD88-dependent toll-like receptor signaling pathway
cellular response to interferon-beta
CD8-positive, alpha-beta T cell differentiation
positive regulation of interleukin-12 biosynthetic process
regulation of innate immune response
negative regulation of regulatory T cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
regulation of cell cycle
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
cellular response to mechanical stimulus
regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein binding