HSS106760

Gene Symbol:

MTHFD1 ZBTB25

Gene Name:

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

zinc finger and BTB domain containing 25

Gene Aliases:

MTHFC, MTHFD

C14orf51, KUP, ZNF46

Chromosome Location:

Chr.14: 64388041 - 64460007 on Build GRCh38

Chromosome Location:

Chr.14: 64447172 - 64505213 on Build GRCh38

UniGene ID:

Hs.652308

Hs.654571

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: MTHFD1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005956.3	NP_005947.3	24	2823
GenBank mRNA	AK302747.1	-	24	2833
	AK312361.1	-	24	2528
	BC001014.2	-	7	721
	BC009806.2	-	24	2489	3508998
	BC050420.1	-	24	2514	5788176
	CA446032.1	-	5	640
	J04031.1	-	24	2489

Gene Symbol: ZBTB25
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001304508.1	NP_001291437.1	3	941
	XM_006720250.3	XP_006720313.1	4	1889
GenBank mRNA	BC014650.1	-	3	941

More Information

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

histidine biosynthetic process
neutrophil homeostasis
neural tube closure
purine nucleotide biosynthetic process
methionine metabolic process
one-carbon metabolic process
heart development
serine family amino acid metabolic process
serine family amino acid biosynthetic process
methionine biosynthetic process
10-formyltetrahydrofolate biosynthetic process
transsulfuration
tetrahydrofolate interconversion
folic acid metabolic process
embryonic neurocranium morphogenesis
embryonic viscerocranium morphogenesis
oxidation-reduction process
somite development
transcription, DNA-templated
regulation of transcription, DNA-templated
gene expression

Function(s)

formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
methylenetetrahydrofolate dehydrogenase (NAD+) activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
protein binding
ATP binding
DNA binding
transcription factor activity, sequence-specific DNA binding
metal ion binding