HSS107529

• Gene Symbol: P2RX7
• Gene Name: purinergic receptor P2X 7
• Gene Aliases: P2X7
• Chromosome Location: Chr.12: 121132819 - 121189478 on Build GRCh38
• UniGene ID: Hs.729169
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: P2RX7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002562.5	NP_002553.3	2, 3	448
	NR_033948.1		3, 4	587
	NR_033949.1		3, 4	587
	NR_033950.1		2, 3	448
	NR_033951.1		2, 3	448
	NR_033952.1		2, 3	448
	NR_033953.1		1, 2	288
	NR_033954.1		2, 3	448
	NR_033955.1		2, 3	448
	NR_033956.1		2, 3	448
	XM_011538419.2	XP_011536721.1	1, 2	288
	XM_011538420.2	XP_011536722.1	1, 2	92
	XM_017019364.1	XP_016874853.1	2, 3	448
	XM_017019365.1	XP_016874854.1	1, 2	176
	XM_017019366.1	XP_016874855.1	2, 3	389
	XM_017019367.1	XP_016874856.1	1, 2	227
GenBank mRNA	AB209709.1	-	2, 3	369
	AK090866.1	-	1, 2	165
	AK225163.1	-	2, 3	334
	AK290405.1	-	2, 3	396
	AK294126.1	-	2, 3	399
	AK296432.1	-	2, 3	396
	AY847298.1	-	2, 3	305
	AY847299.1	-	2, 3	305
	AY847300.1	-	2, 3	305
	AY847301.1	-	2, 3	305
	AY847302.1	-	2, 3	305
	AY847303.1	-	3, 4	444
	AY847304.1	-	3, 4	444
	BC007679.2	-	2, 3	346	3628076
	BC011913.2	-	2, 3	374	4298811
	BC121157.1	-	2, 3	374
	BC121158.1	-	2, 3	374
	BI598073.1	-	2, 3	438
	DA274887.1	-	3, 4	473
	DA302256.1	-	1, 2	288
	DQ399293.1	-	2, 3	305
	GQ180122.1	-	2, 3	314
	Y09561.1	-	2, 3	331

More Information

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

activation of MAPK activity
cell morphogenesis
phagolysosome assembly
positive regulation of T cell mediated cytotoxicity
regulation of sodium ion transport
protein phosphorylation
membrane protein ectodomain proteolysis
phospholipid transfer to membrane
membrane budding
inflammatory response
mitochondrion organization
cell surface receptor signaling pathway
blood coagulation
response to mechanical stimulus
response to zinc ion
positive regulation of calcium ion transport into cytosol
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of gamma-aminobutyric acid secretion
synaptic vesicle exocytosis
protein processing
phospholipid scrambling
sensory perception of pain
cytolysis
positive regulation of bone mineralization
cellular response to extracellular stimulus
bleb assembly
positive regulation of prostaglandin secretion
response to lipopolysaccharide
positive regulation of interleukin-6 production
collagen metabolic process
response to ATP
response to fluid shear stress
positive regulation of ion transmembrane transport
purinergic nucleotide receptor signaling pathway
T cell proliferation
response to drug
T cell homeostasis
NAD transport
negative regulation of MAPK cascade
multicellular organismal protein catabolic process
phospholipid translocation
negative regulation of bone resorption
negative regulation of cell volume
positive regulation of glycolytic process
positive regulation of cytolysis
ceramide biosynthetic process
pore complex assembly
skeletal system morphogenesis
homeostasis of number of cells within a tissue
positive regulation of interleukin-1 alpha secretion
positive regulation of interleukin-1 beta secretion
defense response to Gram-positive bacterium
release of sequestered calcium ion into cytosol
protein oligomerization
positive regulation of cytoskeleton organization
response to calcium ion
response to electrical stimulus
regulation of killing of cells of other organism
membrane depolarization
positive regulation of mitochondrial depolarization
positive regulation of lymphocyte apoptotic process
cellular response to dsRNA
reactive oxygen species metabolic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
positive regulation of bleb assembly

Function(s)

lipopolysaccharide binding
purinergic nucleotide receptor activity
extracellular ATP-gated cation channel activity
receptor binding
protein binding
ATP binding
protein homodimerization activity