HSS107569

• Gene Symbol: SERPINE1
• Gene Name: serpin family E member 1
• Gene Aliases: PAI, PAI-1, PAI1, PLANH1
• Chromosome Location: Chr.7: 101127087 - 101139266 on Build GRCh38
• UniGene ID: Hs.414795
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SERPINE1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000602.4	NP_000593.1	2	212
	XM_017012260.1	XP_016867749.1	2	214
GenBank mRNA	AK297728.1	-	2	199
	BC010860.1	-	2	177	3893914
	CN309001.1	-	2	213
	M16006.1	-	2	130
	X04429.1	-	2	181
	X04729.1	-	2	198
	X12701.1	-	2	181

More Information

Panther Classification:

Molecular Function -

calmodulin-related, protease inhibitor

Gene Ontology Categories:

Process(es)

chronological cell aging
angiogenesis
platelet degranulation
circadian rhythm
regulation of receptor activity
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
negative regulation of smooth muscle cell migration
positive regulation of blood coagulation
negative regulation of blood coagulation
extracellular matrix organization
negative regulation of cell migration
positive regulation of interleukin-8 production
negative regulation of cell adhesion mediated by integrin
positive regulation of leukotriene production involved in inflammatory response
fibrinolysis
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of receptor-mediated endocytosis
positive regulation of inflammatory response
defense response to Gram-negative bacterium
negative regulation of fibrinolysis
negative regulation of vascular wound healing
negative regulation of wound healing
cellular response to lipopolysaccharide
positive regulation of monocyte chemotaxis
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of smooth muscle cell-matrix adhesion
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding