HSS108456

• Gene Symbol: PRKAA1
• Gene Name: protein kinase AMP-activated catalytic subunit alpha 1
• Gene Aliases: AMPK, AMPKa1
• Chromosome Location: Chr.5: 40759379 - 40798195 on Build GRCh38
• UniGene ID: Hs.43322
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PRKAA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006251.5	NP_006242.5	7	905
	NM_206907.3	NP_996790.3	8	950
	XM_006714482.1	XP_006714545.1	6	799
	XM_017009624.1	XP_016865113.1	8	1861
	XM_017009625.1	XP_016865114.1	7	1806
GenBank mRNA	AB022017.1	-	7	895
	AF100763.1	-	7	875
	AK307546.1	-	8	932
	AK312947.1	-	7	887
	BC037303.2	-	7	887	5265054
	BC048980.1	-	8	1129	4839033

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019142, U40819.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
response to hypoxia
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
fatty acid biosynthetic process
cholesterol biosynthetic process
cell cycle arrest
signal transduction
positive regulation of cell proliferation
lipid biosynthetic process
response to UV
cold acclimation
response to gamma radiation
positive regulation of autophagy
positive regulation of gene expression
response to activity
Wnt signaling pathway
macroautophagy
fatty acid oxidation
response to caffeine
cellular response to nutrient levels
negative regulation of TOR signaling
regulation of peptidyl-serine phosphorylation
histone-serine phosphorylation
intracellular signal transduction
cellular response to glucose starvation
glucose homeostasis
regulation of circadian rhythm
negative regulation of apoptotic process
positive regulation of cholesterol biosynthetic process
positive regulation of glycolytic process
negative regulation of glucosylceramide biosynthetic process
rhythmic process
positive regulation of skeletal muscle tissue development
negative regulation of lipid catabolic process
protein heterooligomerization
fatty acid homeostasis
regulation of vesicle-mediated transport
cellular response to hydrogen peroxide
cellular response to ethanol
cellular response to prostaglandin E stimulus
cellular response to organonitrogen compound
cellular response to hypoxia
response to camptothecin
regulation of signal transduction by p53 class mediator
regulation of energy homeostasis
negative regulation of glucose import in response to insulin stimulus

Function(s)

chromatin binding
protein kinase activity
AMP-activated protein kinase activity
cAMP-dependent protein kinase activity
protein binding
ATP binding
protein C-terminus binding
kinase binding
histone serine kinase activity
metal ion binding
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
tau-protein kinase activity
[acetyl-CoA carboxylase] kinase activity