HSS109061

Gene Symbol:

RARA LOC100131821 PML

Gene Name:

retinoic acid receptor alpha

uncharacterized LOC100131821

promyelocytic leukemia

Gene Aliases:

NR1B1, RAR

-

MYL, PP8675, RNF71, TRIM19

Chromosome Location:

Chr.17: 40309171 - 40357643 on Build GRCh38

Chromosome Location:

-

Chromosome Location:

Chr.15: 73994673 - 74047819 on Build GRCh38

UniGene ID:

Hs.654583

Hs.654583

Hs.526464

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: RARA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000964.3	NP_000955.1	3	676
	NM_001024809.3	NP_001019980.1	2	869
	NM_001145301.2	NP_001138773.1	3	788
	XM_005257552.4	XP_005257609.1	2	246
	XM_005257553.1	XP_005257610.1	3	580
	XM_005257554.1	XP_005257611.1	3	829
	XM_011525095.1	XP_011523397.1	4	726
	XM_011525096.1	XP_011523398.1	2	39
	XM_017024920.1	XP_016880409.1	2	148
GenBank mRNA	AK098172.1	-	2	248
	AK130192.1	-	3	712
	AK292205.1	-	3	728
	AK303868.1	-	2	537
	AK312564.1	-	3	652
	AL522713.3	-	3	730
	AL834159.1	-	2	530
	BC008727.2	-	3	653	3163891
	BC071733.1	-	2	472	5217484
	CR457438.1	-	2	198
	HQ692826.1	-	2	198
	HQ692827.1	-	2	183
	S50916.1	-		60
	X06538.1	-	2	424
	X06614.1	-	2	300
	X58685.1	-	1	20

Gene Symbol: LOC100131821
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK123052.1	-	1	2201

Gene Symbol: PML
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	EF535849.1	-		147

More Information

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
neural tube closure
liver development
glandular epithelial cell development
outflow tract septum morphogenesis
growth plate cartilage development
transcription initiation from RNA polymerase II promoter
protein phosphorylation
signal transduction
germ cell development
spermatogenesis
female pregnancy
positive regulation of cell proliferation
negative regulation of cell proliferation
hippocampus development
prostate gland development
negative regulation of granulocyte differentiation
embryonic camera-type eye development
regulation of myelination
response to estradiol
response to retinoic acid
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
response to vitamin A
response to cytokine
multicellular organism growth
negative regulation of apoptotic process
apoptotic cell clearance
steroid hormone mediated signaling pathway
response to ethanol
positive regulation of T-helper 2 cell differentiation
positive regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
regulation of synaptic plasticity
retinoic acid receptor signaling pathway
positive regulation of binding
ventricular cardiac muscle cell differentiation
Sertoli cell fate commitment
limb development
face development
trachea cartilage development
chondroblast differentiation
negative regulation of cartilage development
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to estrogen stimulus

Function(s)

translation repressor activity, nucleic acid binding
RNA polymerase II regulatory region sequence-specific DNA binding
retinoic acid binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
retinoic acid receptor activity
transcription coactivator activity
transcription corepressor activity
receptor binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein domain specific binding
chromatin DNA binding
histone deacetylase binding
protein kinase B binding
retinoic acid-responsive element binding
protein heterodimerization activity
mRNA 5'-UTR binding
protein kinase A binding
alpha-actinin binding