HSS109295

• Gene Symbol: RORA
• Gene Name: RAR related orphan receptor A
• Gene Aliases: NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA
• Chromosome Location: Chr.15: 60488284 - 61229303 on Build GRCh38
• UniGene ID: Hs.560343
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RORA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002943.3	NP_002934.1	8	1372
	NM_134260.2	NP_599022.1	9	1396
	NM_134261.2	NP_599023.1	8	1226
	NM_134262.2	NP_599024.1	7	1067
	XM_005254584.4	XP_005254641.1	8	5687
	XM_011521874.1	XP_011520176.1	7	1264
	XM_011521875.1	XP_011520177.1	8	1096
	XM_011521877.2	XP_011520179.1	7	1299
	XM_011521878.1	XP_011520180.1	9	1138
	XM_011521879.2	XP_011520181.1	5	1024
	XM_017022466.1	XP_016877955.1	7	3088
	XM_017022467.1	XP_016877956.1	7	2761
GenBank mRNA	AB307694.1	-	8	1141
	BC008831.2	-	8	1149	4121602
	BC100987.2	-	7	1017	40005784
	BC100988.1	-	7	1017	40005785
	BC100989.1	-	7	1017	40005786
	BC100990.2	-	7	1017	40005787
	HQ692818.1	-	7	976
	HQ709174.1	-	7	973
	L14611.1	-	7	997
	U04897.1	-	8	1242
	U04898.1	-	9	1329
	U04899.1	-	8	1294

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008766409, XM_008766408, XM_008766410.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

angiogenesis
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
xenobiotic metabolic process
nitric oxide biosynthetic process
regulation of smoothened signaling pathway
positive regulation of vascular endothelial growth factor production
regulation of glucose metabolic process
regulation of steroid metabolic process
cerebellar Purkinje cell differentiation
cerebellar granule cell precursor proliferation
intracellular receptor signaling pathway
circadian regulation of gene expression
cellular response to sterol
muscle cell differentiation
positive regulation of circadian rhythm
regulation of macrophage activation
negative regulation of I-kappaB kinase/NF-kappaB signaling
steroid hormone mediated signaling pathway
negative regulation of fat cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cGMP metabolic process
negative regulation of inflammatory response
regulation of transcription involved in cell fate commitment
triglyceride homeostasis
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to hypoxia
T-helper 17 cell differentiation
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcription corepressor binding
transcription coactivator binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
beta-catenin binding
transcription factor binding
oxysterol binding
zinc ion binding
sequence-specific DNA binding
transcription factor activity, direct ligand regulated sequence-specific DNA binding