HSS109389

• Gene Symbol: RRM1
• Gene Name: ribonucleotide reductase catalytic subunit M1
• Gene Aliases: R1, RIR1, RR1
• Chromosome Location: Chr.11: 4094685 - 4138925 on Build GRCh38
• UniGene ID: Hs.445705
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RRM1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033.4	NP_001024.1	18	2491
	NM_001318064.1	NP_001304993.1	17	2313
	NM_001318065.1	NP_001304994.1	12	1838
	XM_011520278.1	XP_011518580.1	12	1791
GenBank mRNA	AK222786.1	-	18	2371
	AK297988.1	-	18	2236
	AK299629.1	-	16	2128
	AK301891.1	-	12	1631
	AK301922.1	-	12	1673
	AK303394.1	-	17	2157
	BC006498.2	-	18	2322	2989344
	X59543.1	-	18	2350
	X59617.1	-	18	2344

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001013236, BC085906.
This siRNA also targets the following transcripts in Mouse: NM_009103, NM_001033, K02927, AK200772, AK209968, and others.

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

mitotic cell cycle
pyrimidine nucleobase metabolic process
DNA replication
male gonad development
deoxyribonucleotide biosynthetic process
response to ionizing radiation
nucleobase-containing small molecule interconversion
cell proliferation in forebrain
protein heterotetramerization
oxidation-reduction process
retina development in camera-type eye

Function(s)

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
protein binding
ATP binding