HSS110136

• Gene Symbol: SPAST
• Gene Name: spastin
• Gene Aliases: ADPSP, FSP2, SPG4
• Chromosome Location: Chr.2: 32063551 - 32157637 on Build GRCh38
• UniGene ID: Hs.468091
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPAST
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014946.3	NP_055761.2	16, 17	1952
	NM_199436.1	NP_955468.1	15, 16	1856
	XM_005264516.4	XP_005264573.1	16, 17	1728
	XM_011533067.2	XP_011531369.1	15, 16	1941
	XM_017004777.1	XP_016860266.1	15, 16	1913
	XM_017004778.1	XP_016860267.1	14, 15	1845
GenBank mRNA	AB029006.1	-	15, 16	1856
	AJ246001.1	-	16, 17	1856
	AK304135.1	-	7, 8	466
	BC150260.1	-	15, 16	1856	9007202

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108702, XM_008764486, XM_008764487, XM_008764488, BC166846.
This siRNA also targets the following transcripts in Mouse: NM_016962, NM_001162870, AJ246002, BC046286, AK129282, and others.

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
microtubule bundle formation
ER to Golgi vesicle-mediated transport
axonogenesis
anterograde axonal transport
metabolic process
exit from mitosis
axonal transport of mitochondrion
positive regulation of microtubule depolymerization
cytoplasmic microtubule organization
nuclear envelope reassembly
positive regulation of cytokinesis
cytokinetic process
protein hexamerization
microtubule severing
mitotic spindle disassembly
protein homooligomerization
membrane fission

Function(s)

protein binding
ATP binding
microtubule binding
microtubule-severing ATPase activity
alpha-tubulin binding
beta-tubulin binding