HSS111356

• Gene Symbol: WNT5A
• Gene Name: Wnt family member 5A
• Gene Aliases: hWNT5A
• Chromosome Location: Chr.3: 55465715 - 55505261 on Build GRCh38
• UniGene ID: Hs.643085
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: WNT5A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256105.1	NP_001243034.1	2, 3	200
	NM_003392.4	NP_003383.2	2, 3	795
	XM_006713324.1	XP_006713387.1	2, 3	155
	XM_011534085.2	XP_011532387.1	5, 6	5784
	XM_011534086.2	XP_011532388.1	5, 6	2408
	XM_011534087.2	XP_011532389.1	2, 3	301
	XM_011534088.2	XP_011532390.1	2, 3	1446
	XM_011534089.1	XP_011532391.1	2, 3	347
	XM_017007127.1	XP_016862616.1	6, 7	5511
	XM_017007128.1	XP_016862617.1	5, 6	2413
GenBank mRNA	AK290375.1	-	2, 3	458
	AK290869.1	-	2, 3	177
	BC064694.1	-	2, 3	456	30346200
	BC074783.2	-	1, 2	142
	DB224740.1	-	2, 3	200
	EF028086.1	-	2, 3	224
	L20861.1	-	1, 2	576

More Information

Panther Classification:

Molecular Function -

intercellular signal molecule

Gene Ontology Categories:

Process(es)

activation of MAPK activity
establishment of planar polarity
somitogenesis
epithelial to mesenchymal transition
positive regulation of endothelial cell proliferation
heart looping
positive regulation of mesenchymal cell proliferation
lens development in camera-type eye
positive regulation of cytokine secretion involved in immune response
type B pancreatic cell development
planar cell polarity pathway involved in axis elongation
optic cup formation involved in camera-type eye development
Wnt signaling pathway, calcium modulating pathway
activation of JUN kinase activity
axon guidance
synapse assembly
hindgut morphogenesis
midgut development
male gonad development
anterior/posterior axis specification, embryo
response to organic substance
positive regulation of endothelial cell migration
positive regulation of peptidyl-threonine phosphorylation
positive regulation of T cell chemotaxis
positive regulation of neuron projection development
Wnt signaling pathway
olfactory bulb interneuron development
neuron differentiation
keratinocyte differentiation
negative regulation of BMP signaling pathway
positive regulation of cGMP metabolic process
prostate gland development
positive regulation of protein binding
activation of protein kinase B activity
response to estradiol
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
positive regulation of peptidyl-serine phosphorylation
response to testosterone
cellular protein localization
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
chemoattraction of serotonergic neuron axon
chemorepulsion of dopaminergic neuron axon
non-canonical Wnt signaling pathway via JNK cascade
negative regulation of fibroblast growth factor receptor signaling pathway
wound healing
embryonic digit morphogenesis
positive regulation of macrophage activation
negative regulation of apoptotic process
estrous cycle
positive regulation of chemokine biosynthetic process
cell fate commitment
establishment of epithelial cell apical/basal polarity
negative regulation of fat cell differentiation
positive regulation of protein catabolic process
positive regulation of angiogenesis
positive regulation of ossification
positive regulation of endocytosis
positive regulation of meiotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of melanin biosynthetic process
positive regulation of fibroblast proliferation
lung alveolus development
paraxial mesoderm formation
notochord morphogenesis
embryonic skeletal system development
genitalia development
negative regulation of axon extension involved in axon guidance
hypophysis morphogenesis
negative regulation of epithelial cell proliferation
positive regulation of interleukin-1 beta secretion
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
cartilage development
response to glucocorticoid
negative regulation of synapse assembly
response to hyperoxia
palate development
convergent extension involved in axis elongation
convergent extension involved in organogenesis
uterus development
cervix development
vagina development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
urinary bladder development
face development
positive regulation of type I interferon-mediated signaling pathway
lateral sprouting involved in mammary gland duct morphogenesis
mesenchymal-epithelial cell signaling
negative regulation of prostatic bud formation
mammary gland branching involved in thelarche
epithelial cell proliferation involved in mammary gland duct elongation
positive regulation of response to cytokine stimulus
regulation of branching involved in mammary gland duct morphogenesis
planar cell polarity pathway involved in gastrula mediolateral intercalation
mesodermal to mesenchymal transition involved in gastrulation
positive regulation of macrophage cytokine production
positive regulation of cartilage development
planar cell polarity pathway involved in outflow tract morphogenesis
planar cell polarity pathway involved in ventricular septum morphogenesis
planar cell polarity pathway involved in cardiac right atrium morphogenesis
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
planar cell polarity pathway involved in pericardium morphogenesis
positive regulation of thymocyte apoptotic process
cellular response to lipopolysaccharide
cellular response to calcium ion
cellular response to retinoic acid
cellular response to interferon-gamma
hematopoietic stem cell proliferation
cellular response to transforming growth factor beta stimulus
negative regulation of mesenchymal cell proliferation
primitive streak formation
positive regulation of protein kinase C signaling
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
activation of GTPase activity
melanocyte proliferation
positive regulation of protein kinase C activity
positive regulation of protein localization to synapse
regulation of cellular protein localization
excitatory synapse assembly
inhibitory synapse assembly
negative regulation of cell proliferation in midbrain
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation
positive regulation of cell-cell adhesion mediated by cadherin
positive regulation of non-canonical Wnt signaling pathway
positive regulation of interleukin-8 secretion

Function(s)

transcription factor activity, sequence-specific DNA binding
frizzled binding
frizzled-2 binding
receptor tyrosine kinase-like orphan receptor binding
cytokine activity
protein binding
protein domain specific binding
transcription regulatory region DNA binding
receptor agonist activity
chemoattractant activity involved in axon guidance