HSS111424

• Gene Symbol: XRCC5
• Gene Name: X-ray repair cross complementing 5
• Gene Aliases: KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
• Chromosome Location: Chr.2: 216109297 - 216206293 on Build GRCh38
• UniGene ID: Hs.388739
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: XRCC5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021141.3	NP_066964.1	13	1561
GenBank mRNA	AK026166.1	-	8	797
	AK096408.1	-	10	1963
	AK222603.1	-	13	1478
	AK290740.1	-	13	1447
	BC019027.2	-	13	1429	4555162
	BC095442.1	-	13	1447	30329657
	J04977.1	-	13	1454
	M30938.1	-	13	1448
	X57500.1	-	10	1110

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

telomere maintenance
double-strand break repair
double-strand break repair via nonhomologous end joining
DNA recombination
transcription, DNA-templated
cell proliferation
positive regulation of type I interferon production
DNA duplex unwinding
negative regulation of transcription, DNA-templated
regulation of smooth muscle cell proliferation
positive regulation of neurogenesis
hematopoietic stem cell differentiation
cellular response to gamma radiation
cellular response to X-ray
establishment of integrated proviral latency
negative regulation of t-circle formation

Function(s)

DNA binding
damaged DNA binding
double-stranded DNA binding
double-stranded telomeric DNA binding
ATP-dependent DNA helicase activity
protein binding
ATP binding
protein C-terminus binding
ubiquitin protein ligase binding
telomeric DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
macromolecular complex binding
5'-deoxyribose-5-phosphate lyase activity