HSS112577

• Gene Symbol: TNFSF11
• Gene Name: tumor necrosis factor superfamily member 11
• Gene Aliases: CD254, ODF, OPGL, OPTB2, RANKL, TNLG6B, TRANCE, hRANKL2, sOdf
• Chromosome Location: Chr.13: 42562736 - 42608013 on Build GRCh38
• UniGene ID: Hs.333791
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFSF11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003701.3	NP_003692.1	5	867
	NM_033012.3	NP_143026.1	7	1028
	XM_011535280.2	XP_011533582.1	5	572
	XM_017020802.1	XP_016876291.1	5	674
	XM_017020803.1	XP_016876292.1	5	521
GenBank mRNA	AB037599.1	-	5	593
	AB061227.1	-	6	675
	AB064268.1	-	6	582
	AB064269.1	-	5	798
	AB064270.1	-	6	736
	AF013171.1	-	4	502
	AF019047.1	-	5	846
	AF053712.1	-	5	902
	BC040889.1	-	7	1028
	BC074823.2	-	5	748	30915538
	BC074890.2	-	5	748	30915245
	BC117286.1	-	5	750	40125837
	BC117288.1	-	5	750	40125839

More Information

Gene Ontology Categories:

Process(es)

ossification
osteoclast proliferation
monocyte chemotaxis
immune response
activation of JUN kinase activity
organ morphogenesis
cytokine-mediated signaling pathway
osteoclast differentiation
tumor necrosis factor-mediated signaling pathway
mammary gland epithelial cell proliferation
positive regulation of homotypic cell-cell adhesion
paracrine signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
bone resorption
positive regulation of osteoclast differentiation
positive regulation of bone resorption
positive regulation of transcription from RNA polymerase II promoter
positive regulation of T cell activation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
positive regulation of corticotropin-releasing hormone secretion
positive regulation of protein kinase B signaling
calcium ion homeostasis
mammary gland alveolus development
ERK1 and ERK2 cascade
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
positive regulation of intracellular signal transduction
positive regulation of osteoclast development

Function(s)

cytokine activity
tumor necrosis factor receptor binding
tumor necrosis factor receptor superfamily binding