HSS112578

• Gene Symbol: TNFSF11
• Gene Name: tumor necrosis factor superfamily member 11
• Gene Aliases: CD254, ODF, OPGL, OPTB2, RANKL, TNLG6B, TRANCE, hRANKL2, sOdf
• Chromosome Location: Chr.13: 42562736 - 42608013 on Build GRCh38
• UniGene ID: Hs.333791
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFSF11
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003701.3	NP_003692.1	5	906
	NM_033012.3	NP_143026.1	7	1067
	XM_011535280.2	XP_011533582.1	5	611
	XM_017020802.1	XP_016876291.1	5	713
	XM_017020803.1	XP_016876292.1	5	560
GenBank mRNA	AB037599.1	-	5	632
	AB061227.1	-	6	714
	AB064268.1	-	6	621
	AB064269.1	-	5	837
	AB064270.1	-	6	775
	AF013171.1	-	4	541
	AF019047.1	-	5	885
	AF053712.1	-	5	941
	BC040889.1	-	7	1067
	BC074823.2	-	5	787	30915538
	BC074890.2	-	5	787	30915245
	BC117286.1	-	5	789	40125837
	BC117288.1	-	5	789	40125839

More Information

Gene Ontology Categories:

Process(es)

ossification
osteoclast proliferation
monocyte chemotaxis
immune response
activation of JUN kinase activity
organ morphogenesis
cytokine-mediated signaling pathway
osteoclast differentiation
tumor necrosis factor-mediated signaling pathway
mammary gland epithelial cell proliferation
positive regulation of homotypic cell-cell adhesion
paracrine signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAP kinase activity
bone resorption
positive regulation of osteoclast differentiation
positive regulation of bone resorption
positive regulation of transcription from RNA polymerase II promoter
positive regulation of T cell activation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein homooligomerization
positive regulation of corticotropin-releasing hormone secretion
positive regulation of protein kinase B signaling
calcium ion homeostasis
mammary gland alveolus development
ERK1 and ERK2 cascade
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
positive regulation of intracellular signal transduction
positive regulation of osteoclast development

Function(s)

cytokine activity
tumor necrosis factor receptor binding
tumor necrosis factor receptor superfamily binding