HSS112849

• Gene Symbol: TNFSF10
• Gene Name: tumor necrosis factor superfamily member 10
• Gene Aliases: APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
• Chromosome Location: Chr.3: 172505508 - 172523507 on Build GRCh38
• UniGene ID: Hs.478275
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFSF10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001190942.1	NP_001177871.1	1	176
	NM_001190943.1	NP_001177872.1	1	144
	NM_003810.3	NP_003801.1	1	176
	NR_033994.1		1	176
GenBank mRNA	AK296085.1	-	1	144
	AK309200.1	-	1	136
	AK312742.1	-	1	144
	BC009795.1	-	1	73
	BC032722.1	-	1	128	5504670
	BT019564.1	-	1	53
	CR456895.1	-	1	53
	DA041872.1	-	1	136
	DA969653.1	-	1	176
	DQ848564.1	-	1	53
	EU183231.1	-	1	53
	U37518.1	-	1	140
	U57059.1	-	1	143

More Information

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
immune response
signal transduction
cell surface receptor signaling pathway
cell-cell signaling
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

receptor binding
cytokine activity
tumor necrosis factor receptor binding
protein binding
metal ion binding