HSS114106

• Gene Symbol: ROCK2
• Gene Name: Rho associated coiled-coil containing protein kinase 2
• Gene Aliases: ROCK-II
• Chromosome Location: Chr.2: 11179759 - 11345407 on Build GRCh38
• UniGene ID: Hs.681743
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ROCK2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321643.1	NP_001308572.1	25	3066
	NM_004850.4	NP_004841.2	25	3522
	XM_005246190.3	XP_005246247.1	25	3556
	XM_011510417.2	XP_011508719.1	25	3021
	XM_017005378.1	XP_016860867.1	25	3553
	XM_017005379.1	XP_016860868.1	25	2951
GenBank mRNA	AB014519.1	-	25	3527
	AK299296.1	-	11	1529
	AK310358.1	-	21	2817
	BC111801.1	-	12	1629	40069866
	D87931.1	-	25	3073

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

cytokinesis
positive regulation of protein phosphorylation
protein phosphorylation
smooth muscle contraction
I-kappaB kinase/NF-kappaB signaling
Rho protein signal transduction
positive regulation of endothelial cell migration
positive regulation of gene expression
positive regulation of centrosome duplication
negative regulation of angiogenesis
regulation of cell adhesion
cortical actin cytoskeleton organization
regulation of actin cytoskeleton organization
negative regulation of myosin-light-chain-phosphatase activity
regulation of circadian rhythm
regulation of keratinocyte differentiation
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
rhythmic process
centrosome duplication
regulation of stress fiber assembly
regulation of focal adhesion assembly
cellular response to testosterone stimulus
establishment of protein localization to plasma membrane
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly
regulation of establishment of cell polarity
regulation of cell motility

Function(s)

protein serine/threonine kinase activity
structural molecule activity
protein binding
ATP binding
Rho GTPase binding
poly(A) RNA binding
metal ion binding
Rho-dependent protein serine/threonine kinase activity