HSS115434

• Gene Symbol: TOB1
• Gene Name: transducer of ERBB2, 1
• Gene Aliases: APRO5, APRO6, PIG49, TOB, TROB, TROB1
• Chromosome Location: Chr.17: 50862223 - 50867978 on Build GRCh38
• UniGene ID: Hs.703321
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TOB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001243877.1	NP_001230806.1	3	1014
	NM_001243885.1	NP_001230814.1	2	825
	NM_005749.3	NP_005740.1	2	1028
GenBank mRNA	AK313904.1	-	3	1015
	AY524047.1	-	1	595
	BC031406.1	-	1	592	5194914
	BC070493.1	-	2	1016	6470511
	BC098415.1	-	2	1020	6480318
	BT019380.1	-	1	585
	BT019381.1	-	1	585
	CR536487.1	-	1	585
	CR541686.1	-	1	585
	D38305.1	-	1	628

More Information

Gene Ontology Categories:

Process(es)

SMAD protein import into nucleus
negative regulation of cell proliferation
positive regulation of signal transduction
negative regulation of translation
negative regulation of BMP signaling pathway
negative regulation of osteoblast differentiation
negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nucleic acid-templated transcription

Function(s)

transcription corepressor activity
SH3/SH2 adaptor activity
protein binding
receptor tyrosine kinase binding
SMAD binding