HSS120660

• Gene Symbol: RABGEF1
• Gene Name: RAB guanine nucleotide exchange factor 1
• Gene Aliases: RABEX5, RAP1, rabex-5
• Chromosome Location: Chr.7: 66682091 - 66811464 on Build GRCh38
• UniGene ID: Hs.530053
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RABGEF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001287060.1	NP_001273989.1	8, 9	1687
	NM_001287061.1	NP_001273990.1	7, 8	1027
	NM_001287062.1	NP_001273991.1	8, 9	1163
	NM_014504.2	NP_055319.1	7, 8	968
GenBank mRNA	AJ250042.1	-	7, 8	891
	AK001702.1	-	4, 5	472
	AK056864.1	-	8, 9	1614
	AK290678.1	-	8, 9	1086
	AK303006.1	-	7, 8	1024
	BC015330.1	-	7, 8	914	4420279
	BT007107.1	-	6, 7	814
	DQ230533.1	-	6, 7	814
	DQ230534.1	-	7, 8	934
	DQ230535.1	-	4, 5	562

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of leukocyte migration
protein targeting to membrane
endocytosis
protein ubiquitination
negative regulation of mast cell degranulation
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
negative regulation of receptor-mediated endocytosis
negative regulation of inflammatory response
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of interleukin-6 secretion
negative regulation of Kit signaling pathway

Function(s)

DNA binding
protein binding
zinc ion binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
ubiquitin protein ligase activity