HSS121808

• Gene Symbol: CRBN
• Gene Name: cereblon
• Gene Aliases: MRT2, MRT2A
• Chromosome Location: Chr.3: 3148490 - 3179717 on Build GRCh38
• UniGene ID: Hs.18925
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CRBN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001173482.1	NP_001166953.1	2	133
	NM_016302.3	NP_057386.2	2	136
	XM_011533791.2	XP_011532093.1	2	123
	XM_011533793.2	XP_011532095.1	2	123
GenBank mRNA	AF117230.1	-	2	100
	AK027507.1	-	2	114
	AK058191.1	-	2	110
	AK312577.1	-	2	114
	AL711072.1	-	2	126
	BC017419.1	-	2	124	4672890
	BC067811.1	-	2	117	5264951
	DB456585.1	-	2	136

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein ubiquitination
negative regulation of protein homooligomerization
negative regulation of ion transmembrane transport
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein homodimerization activity

Function(s)

ATP-dependent peptidase activity
protein binding
metal ion binding