HSS124761

• Gene Symbol: HIF1AN
• Gene Name: hypoxia inducible factor 1 alpha subunit inhibitor
• Gene Aliases: FIH1
• Chromosome Location: Chr.10: 100535884 - 100553924 on Build GRCh38
• UniGene ID: Hs.500788
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HIF1AN
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017902.2	NP_060372.2	7	1044
	XM_011539940.2	XP_011538242.1	7	1055
	XM_011539941.1	XP_011538243.1	7	922
GenBank mRNA	AF395830.1	-	7	979
	AK000622.1	-	7	989
	AK025680.1	-	3	203
	AK295353.1	-	7	1071
	AL359615.1	-	6	707
	BC007719.2	-	7	972	4138066

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001113749, BC158810.
This siRNA also targets the following transcripts in Mouse: NM_176958, AK141867, BC130013, CN535711, AK154774.

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
peptidyl-histidine hydroxylation
peptidyl-aspartic acid hydroxylation
peptidyl-asparagine hydroxylation
positive regulation of myoblast differentiation
negative regulation of Notch signaling pathway
oxidation-reduction process
regulation of transcription from RNA polymerase II promoter in response to hypoxia
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
positive regulation of vasculogenesis

Function(s)

Notch binding
iron ion binding
protein binding
zinc ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxygen sensor activity
carboxylic acid binding
peptidyl-histidine dioxygenase activity
peptidyl-asparagine 3-dioxygenase activity
protein homodimerization activity
cofactor binding
NF-kappaB binding
ankyrin repeat binding