HSS124925

• Gene Symbol: EDEM2
• Gene Name: ER degradation enhancing alpha-mannosidase like protein 2
• Gene Aliases: C20orf31, C20orf49, bA4204.1
• Chromosome Location: Chr.20: 35115357 - 35147358 on Build GRCh38
• UniGene ID: Hs.720177
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EDEM2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145025.1	NP_001138497.1	9, 10	1217
	NM_018217.2	NP_060687.2	10, 11	1328
	NR_026728.1		9, 10	1544
GenBank mRNA	AK001645.1	-	10, 11	1310
	AK023931.1	-	10, 11	1298
	AK096016.1	-	8, 9	1238
	AK293583.1	-	9, 10	1199
	AK298794.1	-	9, 10	1286
	AK300212.1	-	9, 10	1172
	AK303816.1	-	8, 9	970
	AY007088.1	-	7, 8	896
	AY358580.1	-	9, 10	1178
	BC001371.2	-	10, 11	1295	3051376
	BC016184.1	-	10, 11	1269	4860424
	CR457266.1	-	10, 11	1228

More Information

Gene Ontology Categories:

Process(es)

N-glycan processing
ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
trimming of terminal mannose on B branch
glycoprotein ERAD pathway
positive regulation of retrograde protein transport, ER to cytosol
endoplasmic reticulum mannose trimming
mannose trimming involved in glycoprotein ERAD pathway

Function(s)

glycoprotein binding
alpha-mannosidase activity
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
calcium ion binding