HSS126652

• Gene Symbol: ALS2
• Gene Name: ALS2, alsin Rho guanine nucleotide exchange factor
• Gene Aliases: ALS2CR6, ALSJ, IAHSP, PLSJ
• Chromosome Location: Chr.2: 201700263 - 201781172 on Build GRCh38
• UniGene ID: Hs.471096
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ALS2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_020919.3	NP_065970.2	7	2053
	XM_006712654.2	XP_006712717.1	7	2630
	XM_006712655.3	XP_006712718.1	3	329
	XM_011511530.2	XP_011509832.1	6	1765
	XM_017004569.1	XP_016860058.1	6	1757
	XM_017004570.1	XP_016860059.1	6	1757
	XM_017004571.1	XP_016860060.1	6	1757
	XM_017004572.1	XP_016860061.1	4	1242
GenBank mRNA	AB046783.2	-	6	1774
	AB053305.1	-	7	1820
	AF391100.1	-	7	1820
	AK291029.1	-	7	1837
	BC029174.1	-	7	1823
	BC071576.1	-	7	1815	30347073
	KU178735.1	-	6	1697
	KU178736.1	-	6	1697

More Information

Gene Ontology Categories:

Process(es)

behavioral fear response
in utero embryonic development
receptor recycling
response to oxidative stress
endosome organization
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
positive regulation of Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
regulation of endosome size
positive regulation of protein serine/threonine kinase activity

Function(s)

guanyl-nucleotide exchange factor activity
Ran guanyl-nucleotide exchange factor activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
protein homodimerization activity
protein serine/threonine kinase activator activity