HSS128477

• Gene Symbol: MUL1
• Gene Name: mitochondrial E3 ubiquitin protein ligase 1
• Gene Aliases: C1orf166, GIDE, MAPL, MULAN, RNF218
• Chromosome Location: Chr.1: 20499448 - 20508483 on Build GRCh38
• UniGene ID: Hs.10101
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MUL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024544.2	NP_078820.2	3	455
	XM_011542137.2	XP_011540439.1	3	1138
GenBank mRNA	AB097015.1	-	3	400
	AK022937.1	-	3	441
	AK303820.1	-	3	711
	AL833889.1	-	3	402
	BC010101.2	-	3	362	3508192
	BC014010.1	-	3	355	4026435
	EU935008.1	-	3	298

More Information

Gene Ontology Categories:

Process(es)

mitochondrial fission
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
activation of JUN kinase activity
negative regulation of mitochondrial fusion
regulation of mitochondrion organization
protein ubiquitination
protein sumoylation
negative regulation of cell growth
protein destabilization
positive regulation of protein sumoylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of innate immune response
negative regulation of defense response to virus by host
protein stabilization
mitochondrion localization
regulation of mitochondrial membrane potential
negative regulation of protein kinase B signaling
negative regulation of type I interferon-mediated signaling pathway
cellular response to exogenous dsRNA
negative regulation of chemokine (C-C motif) ligand 5 production
positive regulation of mitochondrial fission
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of dendrite extension

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
identical protein binding