HSS140747

• Gene Symbol: EIF2AK4
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 4
• Gene Aliases: GCN2, PVOD2
• Chromosome Location: Chr.15: 39934101 - 40035596 on Build GRCh38
• UniGene ID: Hs.656673
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: EIF2AK4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001013703.3	NP_001013725.2	38	4857
	XM_005254392.2	XP_005254449.1	37	4811
	XM_011521599.2	XP_011519901.1	36	4766
	XM_011521600.2	XP_011519902.1	37	4709
	XM_017022219.1	XP_016877708.1	35	4595
GenBank mRNA	AB037759.1	-	34	4323
	AJ243428.1	-	16	1484
	AK027011.1	-	24	2295
	AK074361.1	-	16	1525
	AL137627.1	-	7	411
	AL137676.1	-	13	1235
	AL157497.1	-	27	2654
	AL832907.1	-	32	4117
	BC009350.2	-	24	2327

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001177806, NM_013719, AK129334, BC072637, AK011380, and others.

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase, non-receptor serine/threonine protein kinase, translational protein

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
adaptive immune response
T cell activation involved in immune response
positive regulation of adaptive immune response
regulation of translational initiation
protein phosphorylation
cell cycle arrest
learning
long-term memory
regulation of translational initiation by eIF2 alpha phosphorylation
viral translation
negative regulation of translational initiation in response to stress
negative regulation of CREB transcription factor activity
cellular response to amino acid starvation
cellular response to UV
eiF2alpha phosphorylation in response to endoplasmic reticulum stress
induction by virus of host autophagy
negative regulation by host of viral genome replication
negative regulation of neuron differentiation
negative regulation of translational initiation
protein autophosphorylation
defense response to virus
regulation of feeding behavior
regulation of eIF2 alpha phosphorylation by amino acid starvation
cellular response to cold
positive regulation of translational initiation in response to starvation
positive regulation of long-term synaptic potentiation
neuron projection extension
cellular response to leucine starvation

Function(s)

tRNA binding
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
ATP binding