HSS140751

• Gene Symbol: MYLK
• Gene Name: myosin light chain kinase
• Gene Aliases: AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
• Chromosome Location: Chr.3: 123612296 - 123884302 on Build GRCh38
• UniGene ID: Hs.477375
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MYLK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001321309.1	NP_001308238.1	33	5636
	NM_053025.3	NP_444253.3	34	5844
	NM_053026.3	NP_444254.3	33	5637
	NM_053027.3	NP_444255.3	33	5691
	NM_053028.3	NP_444256.3	32	5484
	XM_011512860.2	XP_011511162.1	31	5562
	XM_011512861.2	XP_011511163.1	30	5361
	XM_017006469.1	XP_016861958.1	17	3120
	XM_017006470.1	XP_016861959.1	16	2108
	XM_017006471.1	XP_016861960.1	16	2161
	XM_017006472.1	XP_016861961.1	4	454
	XM_017006473.1	XP_016861962.1	4	403
GenBank mRNA	AB037663.1	-	17	2920
	AF069601.2	-	31	5474
	AF069602.1	-	31	5525
	AF069603.1	-	30	5318
	AF069604.1	-	11	1500
	AF096773.1	-	3	478
	AF096774.1	-	3	475
	AF096775.1	-	3	478
	AK127437.1	-	1	1367
	AK300610.1	-	16	2094
	AK314412.1	-	3	489
	AK314443.1	-	3	532
	AY339601.1	-	31	5562
	AY424269.1	-	30	5357
	AY424270.1	-	31	5564
	BC017811.1	-	3	499
	BC064420.1	-	3	518
	BC100761.2	-	3	360
	BC100762.1	-	3	360
	BC100763.1	-	3	357
	BC107783.1	-	3	502
	BC113456.1	-	3	323
	BC113458.1	-	3	320
	CR749364.1	-	3	5304
	U48959.2	-	32	5681
	X85337.1	-	18	3174
	X90870.1	-	9	1194

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001105874, XM_006248433, XM_008768712, XM_008768711, XM_006248434.
This siRNA also targets the following transcripts in Mouse: NM_139300, AY237727, BC058610, AK078556, AK143973, and others.

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
protein phosphorylation
muscle contraction
smooth muscle contraction
tonic smooth muscle contraction
positive regulation of cell migration
bleb assembly
positive regulation of calcium ion transport
aorta smooth muscle tissue morphogenesis
cellular hypotonic response
positive regulation of wound healing
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

actin binding
myosin light chain kinase activity
protein binding
calmodulin binding
ATP binding
metal ion binding