HSS141354

• Gene Symbol: BAX
• Gene Name: BCL2 associated X, apoptosis regulator
• Gene Aliases: BCL2L4
• Chromosome Location: Chr.19: 48954825 - 48961798 on Build GRCh38
• UniGene ID: Hs.624291
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BAX
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001291428.1	NP_001278357.1	2	116
	NM_004324.3	NP_004315.1	2	116
	NM_138761.3	NP_620116.1	2	116
	NM_138763.3	NP_620118.1	2	116
	NM_138764.4	NP_620119.2	2	116
	NR_027882.1		2	116
	XM_017027077.1	XP_016882566.1	2	125
GenBank mRNA	AF007826.1	-	2	47
	AF247393.1	-	2	47
	AJ417988.1	-	1	26
	AK291076.1	-	2	96
	BC014175.2	-	2	99	4578562
	BE396495.1	-	2	116
	CN281003.1	-	2	69
	L22473.1	-	2	47
	L22474.1	-	2	47
	U19599.1	-	2	47

More Information

Gene Ontology Categories:

Process(es)

ovarian follicle development
neuron migration
T cell homeostatic proliferation
B cell homeostasis
B cell apoptotic process
kidney development
release of cytochrome c from mitochondria
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
blood vessel remodeling
myeloid cell homeostasis
B cell negative selection
B cell homeostatic proliferation
positive regulation of B cell apoptotic process
glycosphingolipid metabolic process
regulation of nitrogen utilization
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
activation of signaling protein activity involved in unfolded protein response
inner mitochondrial membrane organization
outer mitochondrial membrane organization
germ cell development
aging
mitochondrial fusion
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
apoptotic mitochondrial changes
fertilization
response to toxic substance
response to salt stress
establishment or maintenance of transmembrane electrochemical gradient
response to gamma radiation
viral process
hypothalamus development
cerebral cortex development
negative regulation of protein binding
positive regulation of protein oligomerization
endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum calcium ion concentration
release of matrix enzymes from mitochondria
negative regulation of peptidyl-serine phosphorylation
regulation of mammary gland epithelial cell proliferation
glial cell apoptotic process
cellular response to UV
ectopic germ cell programmed cell death
response to cocaine
odontogenesis of dentin-containing tooth
response to drug
regulation of apoptotic process
positive regulation of apoptotic process
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
mitochondrial fragmentation involved in apoptotic process
development of secondary sexual characteristics
cellular respiration
retinal cell programmed cell death
response to copper ion
positive regulation of developmental pigmentation
negative regulation of fibroblast proliferation
spermatid differentiation
post-embryonic camera-type eye morphogenesis
response to axon injury
homeostasis of number of cells within a tissue
protein oligomerization
protein homooligomerization
positive regulation of release of sequestered calcium ion into cytosol
neuron apoptotic process
response to corticosterone
regulation of mitochondrial membrane potential
Sertoli cell proliferation
retina development in camera-type eye
positive regulation of apoptotic process involved in mammary gland involution
vagina development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
thymocyte apoptotic process
mitochondrion morphogenesis
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
intrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
positive regulation of endoplasmic reticulum unfolded protein response
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
apoptotic process involved in patterning of blood vessels
apoptotic process involved in embryonic digit morphogenesis
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
positive regulation of apoptotic DNA fragmentation
positive regulation of IRE1-mediated unfolded protein response
B cell receptor apoptotic signaling pathway
negative regulation of apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
lipid binding
channel activity
heat shock protein binding
protein complex binding
identical protein binding
protein homodimerization activity
protein heterodimerization activity
chaperone binding
BH3 domain binding