HSS142023

• Gene Symbol: FKBP1B
• Gene Name: FK506 binding protein 1B
• Gene Aliases: FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase
• Chromosome Location: Chr.2: 24033205 - 24067743 on Build GRCh38
• UniGene ID: Hs.709461
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FKBP1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001322963.1	NP_001309892.1	5	503
	NM_001322964.1	NP_001309893.1	4	322
	NM_004116.4	NP_004107.1	4	435
	NM_054033.3	NP_473374.1	4	480
	NR_136536.1		6	637
	NR_136538.1		5	569
	NR_136539.1		4	367
	XM_017003593.1	XP_016859082.1	6	538
	XM_017003594.1	XP_016859083.1	4	302
	XM_017003595.1	XP_016859084.1	3	283
	XM_017003596.1	XP_016859085.1	5	529
GenBank mRNA	AF322070.1	-	4	372
	BC002614.1	-	4	423	3161896
	BF216711.1	-	4	289
	BF969580.1	-	4	422
	BI546013.1	-	4	399
	BM802489.1	-	4	480
	BU147063.1	-	4	318
	BU508033.1	-	4	399
	D38037.1	-	4	358
	L37086.1	-	4	352
	S69815.1	-	4	358

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022675, XM_006239860, D86642.
This siRNA also targets the following transcripts in Mouse: NM_016863, BC061121, AF060872, AK005201, AB285017, and others.

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein peptidyl-prolyl isomerization
'de novo' protein folding
smooth muscle contraction
response to glucose
negative regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
neuronal action potential propagation
protein maturation by protein folding
insulin secretion
negative regulation of protein phosphatase type 2B activity
response to vitamin E
ion transmembrane transport
calcium-mediated signaling using intracellular calcium source
protein refolding
T cell proliferation
response to hydrogen peroxide
positive regulation of axon regeneration
negative regulation of release of sequestered calcium ion into cytosol
positive regulation of sequestering of calcium ion
regulation of cytosolic calcium ion concentration
response to redox state
regulation of ryanodine-sensitive calcium-release channel activity
negative regulation of ryanodine-sensitive calcium-release channel activity
chaperone-mediated protein folding
negative regulation of insulin secretion involved in cellular response to glucose stimulus
cell communication by electrical coupling involved in cardiac conduction
regulation of cardiac conduction

Function(s)

peptidyl-prolyl cis-trans isomerase activity
receptor binding
ryanodine-sensitive calcium-release channel activity
protein binding
FK506 binding
calcium channel inhibitor activity
cyclic nucleotide binding
ion channel binding