HSS142056

• Gene Symbol: FOXC2
• Gene Name: forkhead box C2
• Gene Aliases: FKHL14, LD, MFH-1, MFH1
• Chromosome Location: Chr.16: 86567251 - 86568933 on Build GRCh38
• UniGene ID: Hs.436448
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: FOXC2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005251.2	NP_005242.1	1	763
GenBank mRNA	BC113437.1	-	1	763	8322489
	BC113439.1	-	1	763	8322491

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001101680.
This siRNA also targets the following transcripts in Mouse: NM_013519, X74040, BC139208, AK146887, S63607, and others.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ossification
patterning of blood vessels
metanephros development
ureteric bud development
somitogenesis
lymphangiogenesis
blood vessel remodeling
transcription from RNA polymerase II promoter
Notch signaling pathway
mesoderm development
heart development
insulin receptor signaling pathway
response to hormone
positive regulation of endothelial cell migration
neural crest cell development
collagen fibril organization
positive regulation of cell adhesion mediated by integrin
embryonic heart tube development
positive regulation of vascular wound healing
camera-type eye development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of organ growth
vascular endothelial growth factor receptor signaling pathway
paraxial mesodermal cell fate commitment
embryonic viscerocranium morphogenesis
artery morphogenesis
regulation of blood vessel size
ventricular cardiac muscle tissue morphogenesis
cardiac muscle cell proliferation
glomerular endothelium development
glomerular visceral epithelial cell differentiation
glomerular mesangial cell development
positive regulation of cell migration involved in sprouting angiogenesis
negative regulation of apoptotic process involved in outflow tract morphogenesis

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
chromatin DNA binding
identical protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding