HSS144935

• Gene Symbol: MBD2
• Gene Name: methyl-CpG binding domain protein 2
• Gene Aliases: DMTase, NY-CO-41
• Chromosome Location: Chr.18: 54151601 - 54224788 on Build GRCh38
• UniGene ID: Hs.25674
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MBD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003927.4	NP_003918.1	1, 2	769
	NM_015832.4	NP_056647.1	1, 2	769
GenBank mRNA	AF072242.1	-	1, 2	769
	AF072246.1	-	1, 2	72
	BC032638.1	-	1, 2	610	5496721
	BQ228712.1	-		488

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001115025, BC158877.
This siRNA also targets the following transcripts in Mouse: NM_010773, AF072243, BC046607, BC057289, BC026698, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chromatin silencing at rDNA
methylation-dependent chromatin silencing
transcription, DNA-templated
positive regulation of Wnt signaling pathway
regulation of cell proliferation
maternal behavior
ATP-dependent chromatin remodeling
cellular protein complex assembly
negative regulation of transcription, DNA-templated

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
satellite DNA binding
mRNA binding
protein binding
methyl-CpG binding
protein domain specific binding
nucleosomal DNA binding
siRNA binding
C2H2 zinc finger domain binding