HSS145494

• Gene Symbol: PSME3
• Gene Name: proteasome activator subunit 3
• Gene Aliases: HEL-S-283, Ki, PA28-gamma, PA28G, PA28gamma, REG-GAMMA
• Chromosome Location: Chr.17: 42833142 - 42843760 on Build GRCh38
• UniGene ID: Hs.152978
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PSME3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001267045.1	NP_001253974.1	11	1379
	NM_005789.3	NP_005780.2	9	1052
	NM_176863.2	NP_789839.1	9	1091
	NR_049772.1		8	939
	XM_011524177.2	XP_011522479.1	9	1061
GenBank mRNA	AK057221.1	-	11	1218
	AK074999.1	-	9	749
	AK292618.1	-	9	777
	AK303211.1	-	8	636
	AK314347.1	-	9	795
	BC001423.2	-	9	779	3139753
	BC002684.1	-	9	758	3606558
	BC008020.1	-	9	710	3537911
	BT019386.1	-	9	562
	CR541745.1	-	9	562
	EU794653.1	-	9	779
	FJ200488.1	-	8	493
	JX156303.1	-	7	310
	U11292.1	-	9	763

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001011894, BC089889, FQ232375.
This siRNA also targets the following transcripts in Mouse: NM_011192, D87911, AK156079, BC005524, AK171348, and others.

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
apoptotic process
positive regulation of endopeptidase activity
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
regulation of proteasomal protein catabolic process
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
regulation of G1/S transition of mitotic cell cycle
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

p53 binding
protein binding
identical protein binding
endopeptidase activator activity
MDM2/MDM4 family protein binding