HSS145538

• Gene Symbol: STUB1
• Gene Name: STIP1 homology and U-box containing protein 1
• Gene Aliases: CHIP, HSPABP2, NY-CO-7, SCAR16, SDCCAG7, UBOX1
• Chromosome Location: Chr.16: 680111 - 682768 on Build GRCh38
• UniGene ID: Hs.592081
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: STUB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001293197.1	NP_001280126.1	2	786
	NM_005861.3	NP_005852.2	2	697
GenBank mRNA	AF039689.1	-	2	338
	AF129085.1	-	2	378
	AF217968.1	-	2	673
	AF432221.1	-	2	393
	BC007545.1	-	2	381	2959735
	BC017178.1	-	2	368	3346811
	BC022788.1	-	2	381	2959735
	BC063617.1	-	2	312	3847168
	CB145452.1	-	2	206

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001025625, CB568781, BC099240.
This siRNA also targets the following transcripts in Mouse: NM_019719, AK045776, AK004464, AK158595, AK002752, and others.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
DNA repair
ubiquitin-dependent protein catabolic process
misfolded or incompletely synthesized protein catabolic process
protein ubiquitination
negative regulation of transforming growth factor beta receptor signaling pathway
ubiquitin-dependent SMAD protein catabolic process
endoplasmic reticulum unfolded protein response
positive regulation of protein ubiquitination
regulation of protein stability
regulation of glucocorticoid metabolic process
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ERAD pathway
ERBB2 signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of ubiquitin-protein transferase activity
protein maturation
protein autoubiquitination
protein K63-linked ubiquitination
cellular response to misfolded protein
positive regulation of chaperone-mediated protein complex assembly

Function(s)

G-protein coupled receptor binding
ubiquitin-protein transferase activity
protein binding
ligase activity
enzyme binding
kinase binding
Hsp70 protein binding
protein binding, bridging
TPR domain binding
ubiquitin protein ligase binding
ubiquitin-ubiquitin ligase activity
protein homodimerization activity
SMAD binding
misfolded protein binding
Hsp90 protein binding
ubiquitin protein ligase activity
ubiquitin protein ligase activity involved in ERAD pathway