HSS147998

Gene Symbol:

YOD1 PFKFB2

Gene Name:

YOD1 deubiquitinase

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Gene Aliases:

DUBA8, OTUD2, PRO0907

PFK-2/FBPase-2

Chromosome Location:

Chr.1: 207043849 - 207052980 on Build GRCh38

Chromosome Location:

Chr.1: 207053275 - 207081023 on Build GRCh38

UniGene ID:

Hs.567533

Hs.282702

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: YOD1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001276320.1	NP_001263249.1	4	629
	NM_018566.3	NP_061036.3	2	603
GenBank mRNA	AK128014.1	-	4	629
	AL833081.2	-	2	535
	BC137166.1	-	2	595	9021163
	BC137167.1	-	2	595	9021164

Gene Symbol: PFKFB2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK302315.1	-	3	145

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001008889, BC107904.
This siRNA also targets the following transcripts in Mouse: NM_001162415, NM_178691, AK044678, BC099948, AK036991, and others.

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

ER-associated ubiquitin-dependent protein catabolic process
endoplasmic reticulum unfolded protein response
protein K29-linked deubiquitination
protein K11-linked deubiquitination
protein K63-linked deubiquitination
protein K48-linked deubiquitination
negative regulation of retrograde protein transport, ER to cytosol
protein K27-linked deubiquitination
protein K33-linked deubiquitination

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
ubiquitin protein ligase binding
metal ion binding
Lys63-specific deubiquitinase activity
ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol
Lys48-specific deubiquitinase activity