HSS173602

• Gene Symbol: DLC1
• Gene Name: DLC1 Rho GTPase activating protein
• Gene Aliases: ARHGAP7, HP, STARD12, p122-RhoGAP
• Chromosome Location: Chr.8: 13083361 - 13604606 on Build GRCh38
• UniGene ID: Hs.134296
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DLC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024767.3	NP_079043.3	2	613
	NM_182643.2	NP_872584.2	2	613
	XM_005273374.1	XP_005273431.1	2	494
	XM_017012951.1	XP_016868440.1	2	364
GenBank mRNA	AB051510.1	-	2	499
	AK024773.1	-	2	458
	AK225098.1	-	2	458
	AK291682.1	-	2	454
	BC049842.1	-	2	580
	BC054511.1	-	2	368	5240161

More Information

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, GTPase-activating protein

Gene Ontology Categories:

Process(es)

neural tube closure
heart morphogenesis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
negative regulation of cell proliferation
regulation of cell shape
hindbrain morphogenesis
actin cytoskeleton organization
negative regulation of cell migration
forebrain development
regulation of actin cytoskeleton organization
negative regulation of Rho protein signal transduction
positive regulation of protein dephosphorylation
positive regulation of GTPase activity
focal adhesion assembly
regulation of small GTPase mediated signal transduction
negative regulation of stress fiber assembly
negative regulation of focal adhesion assembly
positive regulation of execution phase of apoptosis

Function(s)

GTPase activator activity
protein binding
lipid binding
SH2 domain binding