HSS174353

• Gene Symbol: CHUK
• Gene Name: conserved helix-loop-helix ubiquitous kinase
• Gene Aliases: IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
• Chromosome Location: Chr.10: 100188298 - 100229610 on Build GRCh38
• UniGene ID: Hs.198998
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CHUK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001278.4	NP_001269.3	12, 13	1437
	NM_001320928.1	NP_001307857.1	12, 13	1437
	XM_017015611.1	XP_016871100.1	12, 13	1437
	XM_017015612.1	XP_016871101.1	12, 13	1437
	XM_017015613.1	XP_016871102.1	2, 3	252
GenBank mRNA	AB209028.1	-	12, 13	1391
	AF009225.1	-	12, 13	1394
	AF012890.1	-	12, 13	1359
	AF080157.1	-	12, 13	1454
	BC092514.1	-	12, 13	1375	3063613
	BM800404.1	-		622
	U22512.1	-	11, 12	1267

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107588, XM_008760418, XM_008760419, XM_006231481, BC168905.
This siRNA also targets the following transcripts in Mouse: NM_007700, NM_001162410, AK035326, AK164236, AK018671, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
skeletal muscle contraction
protein phosphorylation
inflammatory response
immune response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
Rho protein signal transduction
response to virus
response to toxic substance
anatomical structure morphogenesis
response to acetate
regulation of tumor necrosis factor-mediated signaling pathway
response to lipopolysaccharide
response to hydroperoxide
TRIF-dependent toll-like receptor signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
response to drug
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
innate immune response
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
striated muscle cell differentiation
stress-activated MAPK cascade
nucleotide-binding oligomerization domain containing signaling pathway
cellular response to tumor necrosis factor

Function(s)

protein kinase activity
protein binding
ATP binding
IkappaB kinase activity
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding