HSS176035

Gene Symbol:

DDIT3 MARS

Gene Name:

DNA damage inducible transcript 3

methionyl-tRNA synthetase

Gene Aliases:

CEBPZ, CHOP, CHOP-10, CHOP10, GADD153

CMT2U, ILFS2, ILLD, METRS, MRS, MTRNS, SPG70

Chromosome Location:

Chr.12: 57516588 - 57520517 on Build GRCh38

Chromosome Location:

Chr.12: 57487953 - 57516655 on Build GRCh38

UniGene ID:

Hs.505777

Hs.632707

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: DDIT3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001195053.1	NP_001181982.1	3	422
	NM_001195054.1	NP_001181983.1	3	369
	NM_001195055.1	NP_001181984.1	3	346
	NM_001195056.1	NP_001181985.1	2	532
	NM_001195057.1	NP_001181986.1	3	251
	NM_004083.5	NP_004074.2	3	265
GenBank mRNA	AA054097.1	-	3	321
	AA476561.1	-	3	272
	AK316581.1	-	2	526
	AV729744.1	-	3	251
	AY461580.1	-	3	424
	BC003637.2	-	3	266	3530545
	BM464290.1	-	3	255
	BT006691.1	-	1	85
	BU664077.1	-	3	363
	CN482428.1	-	3	229
	S40706.1	-	3	256

Gene Symbol: MARS
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK122956.1	-	23	3341

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel maturation
response to amphetamine
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
ER overload response
response to unfolded protein
cell cycle arrest
aging
response to nutrient
Wnt signaling pathway
positive regulation of interleukin-8 production
negative regulation of CREB transcription factor activity
response to endoplasmic reticulum stress
PERK-mediated unfolded protein response
ATF6-mediated unfolded protein response
response to drug
response to hydrogen peroxide
response to starvation
mRNA transcription from RNA polymerase II promoter
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
regulation of DNA-templated transcription in response to stress
regulation of transcription involved in anterior/posterior axis specification
cell redox homeostasis
negative regulation of fat cell differentiation
negative regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic organ development
release of sequestered calcium ion into cytosol
negative regulation of protein kinase B signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
negative regulation of canonical Wnt signaling pathway
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
negative regulation of determination of dorsal identity

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
transcription factor binding
cAMP response element binding protein binding
protein homodimerization activity
leucine zipper domain binding
transcription regulatory region DNA binding
protein heterodimerization activity