HSS179148

• Gene Symbol: A2M
• Gene Name: alpha-2-macroglobulin
• Gene Aliases: A2MD, CPAMD5, FWP007, S863-7
• Chromosome Location: Chr.12: 9067708 - 9115962 on Build GRCh38
• UniGene ID: Hs.212838
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: A2M
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000014.4	NP_000005.2	21, 22	2823
	XM_006719056.2	XP_006719119.1	21, 22	2801
GenBank mRNA	AB209614.2	-	21, 22	2734
	AK307832.1	-	20, 21	2560
	AK312482.1	-	21, 22	2723
	AY591530.1	-	21, 22	2788
	BC040071.1	-	21, 22	2762	6056126
	BX647329.1	-	4, 5	500
	BX648622.1	-		2207
	CR749334.1	-	21, 22	2781
	M11313.1	-	21, 22	2753
	M36501.1	-	2, 3	217

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of complement activation, lectin pathway
platelet degranulation
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
extracellular matrix disassembly
positive regulation of GTPase activity
stem cell differentiation
regulation of small GTPase mediated signal transduction

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
GTPase activator activity
receptor binding
protein binding
growth factor binding
enzyme binding
interleukin-8 binding
interleukin-1 binding
tumor necrosis factor binding
calcium-dependent protein binding