HSS180125

• Gene Symbol: KCNH2
• Gene Name: potassium voltage-gated channel subfamily H member 2
• Gene Aliases: ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1
• Chromosome Location: Chr.7: 150944956 - 150978314 on Build GRCh38
• UniGene ID: Hs.647099
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: KCNH2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000238.3	NP_000229.1	7	2185
	NM_001204798.1	NP_001191727.1	3	1090
	NM_172056.2	NP_742053.1	7	2185
	NM_172057.2	NP_742054.1	3	1090
	XM_011516185.2	XP_011514487.1	6	1596
	XM_011516186.2	XP_011514488.1	7	2177
	XM_017012195.1	XP_016867684.1	6	2266
	XM_017012196.1	XP_016867685.1	7	1726
GenBank mRNA	AB044806.1	-	7	1967
	AF363636.1	-	7	1784
	AJ512214.1	-	3	781
	AJ609614.1	-	3	764
	AY927502.1	-	1	31
	BC001914.1	-	6	1441
	BC127673.1	-	3	1079
	BT007336.1	-	6	1436
	DQ525913.1	-	7	2185
	FJ938021.1	-	5	2617
	U04270.1	-	7	1967

More Information

Panther Classification:

Molecular Function -

ion channel

Gene Ontology Categories:

Process(es)

phosphorelay signal transduction system
regulation of heart rate by hormone
signal transduction by protein phosphorylation
cellular response to drug
regulation of membrane potential
potassium ion homeostasis
cardiac muscle contraction
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
potassium ion export
potassium ion transmembrane transport
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane repolarization during action potential
membrane repolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transport
negative regulation of potassium ion transmembrane transport
positive regulation of potassium ion transmembrane transport
negative regulation of potassium ion export

Function(s)

phosphorelay sensor kinase activity
inward rectifier potassium channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
protein binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
C3HC4-type RING finger domain binding
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
scaffold protein binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization