HSS180974

• Gene Symbol: ARRB1
• Gene Name: arrestin beta 1
• Gene Aliases: ARB1, ARR1
• Chromosome Location: Chr.11: 75260122 - 75351831 on Build GRCh38
• UniGene ID: Hs.503284
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARRB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004041.4	NP_004032.2	15	1339
	NM_020251.3	NP_064647.1	14	1315
	XM_011545034.2	XP_011543336.1	16	1223
	XM_011545035.2	XP_011543337.1	15	1199
	XM_017017750.1	XP_016873239.1	16	1223
	XM_017017751.1	XP_016873240.1	15	1199
	XM_017017752.1	XP_016873241.1	15	1179
	XM_017017753.1	XP_016873242.1	15	1243
	XM_017017754.1	XP_016873243.1	14	1155
GenBank mRNA	AF084040.1	-	15	1115
	AF084940.1	-	14	1091
	AK289718.1	-	15	1169
	BC003636.2	-	15	1192	3604829
	BX402200.2	-	2	568
	FJ348262.1	-	14	1091
	L04685.1	-	15	1115

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

activation of MAPK activity
positive regulation of protein phosphorylation
G-protein coupled receptor internalization
positive regulation of receptor internalization
transcription from RNA polymerase II promoter
apoptotic process
phototransduction
protein transport
protein ubiquitination
platelet activation
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein binding
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
negative regulation of GTPase activity
positive regulation of smooth muscle cell apoptotic process
positive regulation of Rho protein signal transduction
positive regulation of histone acetylation
positive regulation of insulin secretion involved in cellular response to glucose stimulus
response to antidepressant
follicle-stimulating hormone signaling pathway
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of histone H4 acetylation

Function(s)

histone acetyltransferase activity
enzyme inhibitor activity
GTPase activator activity
insulin-like growth factor receptor binding
protein binding
transcription factor binding
estrogen receptor binding
mitogen-activated protein kinase kinase binding
ubiquitin protein ligase binding
alpha-1A adrenergic receptor binding
alpha-1B adrenergic receptor binding
angiotensin receptor binding
follicle-stimulating hormone receptor binding
V2 vasopressin receptor binding
AP-2 adaptor complex binding
clathrin adaptor activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
transcription regulatory region DNA binding
ion channel binding
protein phosphorylated amino acid binding