HSS181360

• Gene Symbol: MSX2
• Gene Name: msh homeobox 2
• Gene Aliases: CRS2, FPP, HOX8, MSH, PFM, PFM1
• Chromosome Location: Chr.5: 174724495 - 174730899 on Build GRCh38
• UniGene ID: Hs.89404
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MSX2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_002449.4	NP_002440.2	1	396
	XM_017009489.1	XP_016864978.1	1	473
GenBank mRNA	AL552909.3	-	1	397
	BC015509.1	-	1	331	3903028
	BT009814.1	-	1	308
	D14970.1	-	1	23
	D26145.1	-	1	331
	D31771.1	-	1	369
	D89377.1	-	1	369
	S75361.1	-	1	369

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012982, BF414483.
This siRNA also targets the following transcripts in Mouse: NM_013601, X59252, BC141132, AK131974, AK133846, and others.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
chondrocyte development
osteoblast development
outflow tract septum morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
endochondral bone growth
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
positive regulation of BMP signaling pathway
negative regulation of CREB transcription factor activity
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
wound healing, spreading of epidermal cells
embryonic nail plate morphogenesis
negative regulation of apoptotic process
negative regulation of fat cell differentiation
negative regulation of keratinocyte differentiation
positive regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
stem cell differentiation
positive regulation of catagen
bone trabecula formation
cranial suture morphogenesis
frontal suture morphogenesis
branching involved in mammary gland duct morphogenesis
BMP signaling pathway involved in heart development
enamel mineralization
cellular response to estradiol stimulus
activation of meiosis
negative regulation of transcription regulatory region DNA binding
positive regulation of mesenchymal cell apoptotic process

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription cofactor activity
protein binding
transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding