HSS181569

• Gene Symbol: ATP2A2
• Gene Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
• Gene Aliases: ATP2B, DAR, DD, SERCA2
• Chromosome Location: Chr.12: 110281227 - 110351093 on Build GRCh38
• UniGene ID: Hs.506759
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ATP2A2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001681.3	NP_001672.1	8	1278
	NM_170665.3	NP_733765.1	8	1278
	XM_005253888.2	XP_005253945.1	8	1273
	XM_011538402.2	XP_011536704.1	8	1273
GenBank mRNA	AK293877.1	-	4	386
	BC035588.1	-	8	825	5503508
	KU177929.1	-	8	715
	M23114.1	-	8	878
	M23115.1	-	8	718

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009722, NM_001110140, BC054748, AK210291, AJ223584, and others.

Panther Classification:

Molecular Function -

primary active transporter

Gene Ontology Categories:

Process(es)

regulation of the force of heart contraction
ER-nucleus signaling pathway
organelle organization
cell adhesion
epidermis development
positive regulation of heart rate
regulation of cardiac muscle contraction by calcium ion signaling
transition between fast and slow fiber
endoplasmic reticulum calcium ion homeostasis
positive regulation of endoplasmic reticulum calcium ion concentration
T-tubule organization
ion transmembrane transport
cellular response to oxidative stress
response to endoplasmic reticulum stress
response to peptide hormone
negative regulation of heart contraction
relaxation of cardiac muscle
sarcoplasmic reticulum calcium ion transport
calcium ion transmembrane transport
regulation of cardiac muscle cell membrane potential
regulation of cardiac muscle cell action potential involved in regulation of contraction
regulation of calcium ion-dependent exocytosis of neurotransmitter
calcium ion transport from cytosol to endoplasmic reticulum
regulation of cardiac conduction
calcium ion import into sarcoplasmic reticulum

Function(s)

calcium-transporting ATPase activity
calcium ion binding
protein binding
ATP binding
protein C-terminus binding
enzyme binding
lutropin-choriogonadotropic hormone receptor binding
S100 protein binding
calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential