HSS181703

• Gene Symbol: RRM2B
• Gene Name: ribonucleotide reductase regulatory TP53 inducible subunit M2B
• Gene Aliases: MTDPS8A, MTDPS8B, P53R2
• Chromosome Location: Chr.8: 102204501 - 102239118 on Build GRCh38
• UniGene ID: Hs.512592
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: RRM2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001172477.1	NP_001165948.1	8	1090
	NM_001172478.1	NP_001165949.1	7	953
	NM_015713.4	NP_056528.2	8	1109
GenBank mRNA	AB036063.1	-	8	1109
	AB163437.1	-	7	709
	AB163438.1	-	3	198
	AB166670.1	-	3	229
	AB166671.1	-	8	865
	AK001965.1	-	8	904
	AK304354.1	-	8	1034
	AL137348.1	-	8	911
	BC042468.1	-	6	667
	BC108261.1	-	8	921	6143754
	BC117496.1	-	8	946	40126047
	BC130628.1	-	8	946	40146659
	BX509409.1	-	2	113
	CR627376.1	-	8	1034

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_199476, AK138731, BC058103.

Panther Classification:

Molecular Function -

reductase

Gene Ontology Categories:

Process(es)

kidney development
renal system process
mitochondrial DNA replication
DNA repair
response to oxidative stress
deoxyribonucleoside diphosphate metabolic process
deoxyribonucleoside triphosphate metabolic process
deoxyribonucleotide biosynthetic process
response to amine
nucleobase-containing small molecule interconversion
oxidation-reduction process
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Function(s)

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
protein binding
metal ion binding