HSS183946

• Gene Symbol: MKL1
• Gene Name: megakaryoblastic leukemia (translocation) 1
• Gene Aliases: BSAC, MAL, MRTF-A
• Chromosome Location: Chr.22: 40410281 - 40636719 on Build GRCh38
• UniGene ID: Hs.654688
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MKL1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001282660.1	NP_001269589.1	12	2806
	NM_001282661.1	NP_001269590.1	14	3068
	NM_001282662.1	NP_001269591.1	15	3228
	NM_001318139.1	NP_001305068.1	13	2943
	NM_020831.4	NP_065882.1	15	3218
	XM_005261692.1	XP_005261749.1	14	3023
	XM_005261694.1	XP_005261751.1	14	3113
	XM_011530283.1	XP_011528585.1	16	3326
	XM_011530285.1	XP_011528587.1	16	3237
	XM_011530287.1	XP_011528589.1	8	2205
	XM_017028888.1	XP_016884377.1	15	3301
	XM_017028889.1	XP_016884378.1	11	4301
GenBank mRNA	AB037859.2	-	15	3190
	AF368061.1	-	15	3143
	AJ297257.1	-	12	2800
	AJ297258.1	-	15	3200
	AL713710.1	-	7	2013
	BC114364.2	-	2	1393
	BC115039.1	-	15	3194	5551767
	BC139730.1	-	13	1971
	CR456522.1	-	12	2617
	HG764171.1	-	13	2943

More Information

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
positive regulation of transcription via serum response element binding
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
smooth muscle cell differentiation
negative regulation of apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
actin binding
actin monomer binding
protein binding
leucine zipper domain binding