HSS185683

• Gene Symbol: SKI
• Gene Name: SKI proto-oncogene
• Gene Aliases: SGS, SKV
• Chromosome Location: Chr.1: 2228695 - 2310213 on Build GRCh38
• UniGene ID: Hs.656507
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SKI
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003036.3	NP_003027.1	1	149
	XM_005244775.3	XP_005244832.1	1	119
GenBank mRNA	X15218.1	-	1	149

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008764420.
This siRNA also targets the following transcripts in Mouse: NM_011385, BC068305, AF435852.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
neural tube closure
lens morphogenesis in camera-type eye
transcription, DNA-templated
transforming growth factor beta receptor signaling pathway
cell proliferation
negative regulation of cell proliferation
anterior/posterior axis specification
negative regulation of Schwann cell proliferation
myotube differentiation
olfactory bulb development
myelination in peripheral nervous system
positive regulation of Wnt signaling pathway
embryonic limb morphogenesis
BMP signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
negative regulation of histone deacetylation
negative regulation of activin receptor signaling pathway
somatic stem cell population maintenance
regulation of apoptotic process
camera-type eye development
positive regulation of DNA binding
nose morphogenesis
negative regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of fibroblast proliferation
camera-type eye morphogenesis
skeletal muscle fiber development
cell motility
palate development
retina development in camera-type eye
face morphogenesis
bone morphogenesis
SMAD protein signal transduction
protein homotrimerization

Function(s)

transcription corepressor activity
protein binding
zinc ion binding
protein kinase binding
protein domain specific binding
ubiquitin protein ligase binding
SMAD binding
histone deacetylase inhibitor activity
repressing transcription factor binding