HSS185875

Gene Symbol:

NCF1 NCF1B NCF1C

Gene Name:

neutrophil cytosolic factor 1

neutrophil cytosolic factor 1B pseudogene

neutrophil cytosolic factor 1C pseudogene

Gene Aliases:

NCF1A, NOXO2, SH3PXD1A, p47phox

NCF-1B, SH3PXD1B

SH3PXD1C

Chromosome Location:

Chr.7: 74773962 - 74789376 on Build GRCh38

Chromosome Location:

Chr.7: 73220639 - 73235945 on Build GRCh38

Chromosome Location:

Chr.7: 75156578 - 75171998 on Build GRCh38

UniGene ID:

Hs.647047

Hs.655201

Hs.647047

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

siRNA Details

Gene Symbol: NCF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000265.5	NP_000256.4	1	101
GenBank mRNA	AK127905.1	-	1	52
	AK223217.1	-	1	52
	AK292094.1	-	1	52
	AK316341.1	-	1	52
	AK316552.1	-	1	52
	BC002816.2	-	1	101	3633829
	BC065731.1	-	1	57	6735930
	U25793.1	-		12

Gene Symbol: NCF1B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_003186.1		1	38
GenBank mRNA	AK298655.1	-	1	54
	BC080194.1	-	1	38

Gene Symbol: NCF1C
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_003187.3		1	86
GenBank mRNA	AF330627.1	-	1	41
	AK298739.1	-	1	52
	AK316329.1	-	1	86
	DC389713.1	-	1	86
	M25665.1	-	1	43
	M55067.1	-	1	53

More Information

Gene Ontology Categories:

Process(es)

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
protein targeting to membrane
superoxide metabolic process
cellular defense response
superoxide anion generation
positive regulation of catalytic activity
innate immune response
cell redox homeostasis
respiratory burst
vascular endothelial growth factor receptor signaling pathway
oxidation-reduction process

Function(s)

protein binding
electron carrier activity
superoxide-generating NADPH oxidase activity
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
phosphatidylinositol binding
phosphatidylinositol-3,4-bisphosphate binding