HSS186148

Gene Symbol:

AURKA AURKAPS1

Gene Name:

aurora kinase A

aurora kinase A pseudogene 1

Gene Aliases:

AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7

AurAps1, STK6P

Chromosome Location:

Chr.20: 56369389 - 56392337 on Build GRCh38

Chromosome Location:

Chr.1: 220266179 - 220267715 on Build GRCh38

UniGene ID:

Hs.250822

Hs.654849

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: AURKA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001323303.1	NP_001310232.1	6	952
	NM_001323304.1	NP_001310233.1	6	715
	NM_001323305.1	NP_001310234.1	7	825
	NM_003600.3	NP_003591.2	5	842
	NM_198433.2	NP_940835.1	7	1050
	NM_198434.2	NP_940836.1	6	741
	NM_198435.2	NP_940837.1	5	631
	NM_198436.2	NP_940838.1	6	727
	NM_198437.2	NP_940839.1	5	617
	XM_017028034.1	XP_016883523.1	7	1172
	XM_017028035.1	XP_016883524.1	5	532
GenBank mRNA	AF008551.1	-	4	442
	AF011468.1	-	5	698
	AK301769.1	-	5	304
	AK312776.1	-	5	509
	BC001280.1	-	6	574	3456017
	BC002499.2	-	5	570	3051177
	BC006423.1	-	5	467	3532438
	BC027464.1	-	6	609	4449474
	BM458030.1	-	6	642
	BQ435059.1	-	5	463
	BU171303.1	-	5	563
	D84212.1	-	6	608

Gene Symbol: AURKAPS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_001587.1		1	240

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
meiotic spindle organization
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
spindle organization
mitotic spindle organization
spindle assembly involved in female meiosis I
mitotic nuclear division
mitotic centrosome separation
anterior/posterior axis specification
anaphase-promoting complex-dependent catabolic process
regulation of protein stability
negative regulation of protein binding
response to estradiol
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of cytokinesis
histone-serine phosphorylation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
positive regulation of mitotic nuclear division
regulation of centrosome cycle
protein autophosphorylation
cell division
centrosome localization
protein localization to centrosome
positive regulation of oocyte maturation
regulation of signal transduction by p53 class mediator
neuron projection extension

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
protein kinase binding
ubiquitin protein ligase binding
histone serine kinase activity