HSS186412

• Gene Symbol: TRAF2
• Gene Name: TNF receptor associated factor 2
• Gene Aliases: MGC:45012, TRAP, TRAP3
• Chromosome Location: Chr.9: 136881776 - 136926615 on Build GRCh38
• UniGene ID: Hs.522506
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TRAF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021138.3	NP_066961.2	5	539
	XM_011518973.2	XP_011517275.1	6	843
	XM_011518974.2	XP_011517276.1	5	1444
	XM_011518975.2	XP_011517277.1	6	771
	XM_011518976.2	XP_011517278.1	6	812
	XM_011518977.2	XP_011517279.1	5	532
	XM_011518978.2	XP_011517280.1	5	1953
	XM_017015094.1	XP_016870583.1	5	587
	XM_017015095.1	XP_016870584.1	5	1297
GenBank mRNA	AK054686.1	-	5	682
	AK222961.1	-	5	536
	AK289722.1	-	6	655
	AK298370.1	-	5	503
	BC032410.1	-	4	525	5216790
	BC033810.1	-	5	527	5182942
	BC043492.1	-	5	539	5767794
	BC064662.1	-	4	534	6528158
	BM785733.1	-	5	539
	BX538160.1	-	5	556
	HM991672.1	-	4	482

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
response to endoplasmic reticulum stress
regulation of apoptotic process
positive regulation of JUN kinase activity
cellular protein complex assembly
positive regulation of T cell activation
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein homotrimerization
protein K63-linked ubiquitination
death-inducing signaling complex assembly
cellular response to nitric oxide
positive regulation of protein homodimerization activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
programmed necrotic cell death
negative regulation of neuron death
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB phosphorylation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
ligase activity
enzyme binding
protein kinase binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
sphingolipid binding