HSS187688

• Gene Symbol: WFS1
• Gene Name: wolframin ER transmembrane glycoprotein
• Gene Aliases: CTRCT41, WFRS, WFS, WFSL
• Chromosome Location: Chr.4: 6260368 - 6303265 on Build GRCh38
• UniGene ID: Hs.518602
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: WFS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001145853.1	NP_001139325.1	8	1773
	NM_006005.3	NP_005996.2	8	1777
	XM_017008586.1	XP_016864075.1	9	1756
GenBank mRNA	AF084481.1	-	8	1777
	AK312897.1	-	8	1706
	BC030130.2	-	8	1707	4127654
	KU178395.1	-	7	1607
	Y18064.1	-	8	1765

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031823, AF136378.
This siRNA also targets the following transcripts in Mouse: NM_011716, AK170180, AF084482, BC046988, AK145023, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
kidney development
renal water homeostasis
ER overload response
visual perception
sensory perception of sound
protein maturation by protein folding
ER-associated ubiquitin-dependent protein catabolic process
positive regulation of protein ubiquitination
endoplasmic reticulum calcium ion homeostasis
response to endoplasmic reticulum stress
IRE1-mediated unfolded protein response
glucose homeostasis
negative regulation of programmed cell death
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron apoptotic process
positive regulation of adenylate cyclase activity
positive regulation of growth
protein stabilization
neurological system process
positive regulation of protein metabolic process
positive regulation of calcium ion transport
calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of ATF6-mediated unfolded protein response
negative regulation of type B pancreatic cell apoptotic process

Function(s)

protein binding
ubiquitin protein ligase binding
activating transcription factor binding
ATPase binding