HSS187878

• Gene Symbol: DDR1
• Gene Name: discoidin domain receptor tyrosine kinase 1
• Gene Aliases: CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
• Chromosome Location: Chr.6: 30880909 - 30900156 on Build GRCh38
• UniGene ID: Hs.631988
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DDR1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001202521.1	NP_001189450.1	6, 7	902
	NM_001202522.1	NP_001189451.1	6, 7	902
	NM_001202523.1	NP_001189452.1	7, 8	1154
	NM_001297652.1	NP_001284581.1	7, 8	1273
	NM_001297653.1	NP_001284582.1	7, 8	1075
	NM_001297654.1	NP_001284583.1	7, 8	1075
	NM_001954.4	NP_001945.3	9, 10	1193
	NM_013993.2	NP_054699.2	8, 9	1119
	NM_013994.2	NP_054700.2	6, 7	902
	XM_006715185.2	XP_006715248.1	7, 8	1066
	XM_011514882.2	XP_011513184.1	7, 8	1066
	XM_011514883.1	XP_011513185.1	9, 10	1181
	XM_011514884.1	XP_011513186.1	9, 10	1257
	XM_011514885.1	XP_011513187.1	7, 8	1104
	XM_011514886.1	XP_011513188.1	7, 8	969
	XM_011514887.1	XP_011513189.1	7, 8	1119
	XM_011514888.2	XP_011513190.1	7, 8	1066
	XM_017011268.1	XP_016866757.1	7, 8	936
	XM_017011269.1	XP_016866758.1	7, 8	1119
GenBank mRNA	AB210021.1	-	8, 9	1014
	AK130776.1	-	2, 3	248
	AK291621.1	-	7, 8	968
	AK294793.1	-	7, 8	1140
	BC008716.2	-	9, 10	1193	2964574
	BC013400.2	-	9, 10	1193	2964574
	BC070070.1	-	7, 8	964	5262509
	L11315.1	-	8, 9	1001
	L20817.1	-	7, 8	1052
	L57508.1	-	7, 8	1052
	X74979.1	-	6, 7	905
	Z29093.1	-	6, 7	1196

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013137, NM_001166022, BC166604.
This siRNA also targets the following transcripts in Mouse: NM_007584, NM_001198833, NM_001198831, NM_172962, AK138698, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

regulation of cell growth
regulation of cell-matrix adhesion
cell adhesion
embryo implantation
lactation
negative regulation of cell proliferation
regulation of extracellular matrix disassembly
smooth muscle cell migration
extracellular matrix organization
organ regeneration
collagen-activated tyrosine kinase receptor signaling pathway
peptidyl-tyrosine autophosphorylation
ear development
skin development
wound healing, spreading of cells
protein autophosphorylation
branching involved in mammary gland duct morphogenesis
mammary gland alveolus development
smooth muscle cell-matrix adhesion

Function(s)

transmembrane receptor protein tyrosine kinase activity
protein binding
collagen binding
ATP binding
protein tyrosine kinase collagen receptor activity
metal ion binding