HSS190426

• Gene Symbol: CLOCK
• Gene Name: clock circadian regulator
• Gene Aliases: KAT13D, bHLHe8
• Chromosome Location: Chr.4: 55427901 - 55547138 on Build GRCh38
• UniGene ID: Hs.436975
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CLOCK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001267843.1	NP_001254772.1	23	3066
	NM_004898.3	NP_004889.1	22	2557
	XM_005265787.2	XP_005265844.1	22	2603
	XM_011534409.2	XP_011532711.1	22	3012
	XM_011534410.2	XP_011532712.1	21	2394
	XM_011534411.2	XP_011532713.1	21	2353
	XM_017008854.1	XP_016864343.1	23	2943
	XM_017008855.1	XP_016864344.1	19	2152
GenBank mRNA	AB002332.1	-	21	2391
	AF011568.1	-	22	2497
	AK124437.1	-	1	1545
	AK223549.1	-	22	2497
	AK291708.1	-	22	2496
	BC041878.1	-	23	3066	5272026
	BC126157.1	-	22	2473	8991873
	BC126159.1	-	22	2473	8991875

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_021856, NM_001289832, XM_006250870, XM_006250869, AB019259, and others.
This siRNA also targets the following transcripts in Mouse: NM_001289826, NM_007715, AK129118, AF000998, BC129886, and others.

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
signal transduction
spermatogenesis
circadian rhythm
photoperiodism
entrainment of circadian clock
histone acetylation
circadian regulation of gene expression
regulation of hair cycle
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of inflammatory response
regulation of insulin secretion
positive regulation of NF-kappaB transcription factor activity
response to redox state
cellular response to ionizing radiation
regulation of type B pancreatic cell development
negative regulation of glucocorticoid receptor signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
histone acetyltransferase activity
protein binding
chromatin DNA binding
sequence-specific DNA binding
protein dimerization activity
E-box binding