HSS190751

• Gene Symbol: MED12
• Gene Name: mediator complex subunit 12
• Gene Aliases: ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230
• Chromosome Location: Chr.X: 71118556 - 71142454 on Build GRCh38
• UniGene ID: Hs.409226
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MED12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005120.2	NP_005111.2	7	1237
GenBank mRNA	AB102668.1	-	4	579
	AF071309.1	-	7	1050
	AK302543.1	-	7	1237
	D83783.1	-	6	879

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001193292, XM_006257104, XM_008773273, XM_008773272.
This siRNA also targets the following transcripts in Mouse: NM_021521, AF071310, BC090654, BC057119, BC145447.

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

neural tube closure
transcription initiation from RNA polymerase II promoter
endoderm development
heart development
oligodendrocyte development
Schwann cell development
protein ubiquitination
stem cell population maintenance
spinal cord development
negative regulation of Wnt signaling pathway
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
post-anal tail morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic neurocranium morphogenesis
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
axis elongation involved in somitogenesis
embryonic brain development

Function(s)

RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription cofactor activity
RNA polymerase II transcription coactivator activity
chromatin binding
transcription cofactor activity
transcription coactivator activity
receptor activity
protein binding
beta-catenin binding
protein C-terminus binding
protein domain specific binding
ligand-dependent nuclear receptor transcription coactivator activity
vitamin D receptor binding
thyroid hormone receptor binding
ubiquitin protein ligase activity