MSS201785

• Gene Symbol: Parp1
• Gene Name: poly (ADP-ribose) polymerase family, member 1
• Gene Aliases: 5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1
• Chromosome Location: Chr.1: 180568975 - 180601254 on Build GRCm38
• UniGene ID: Mm.277779
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Parp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007415.2	NP_031441.2	4	534
GenBank mRNA	AK028042.1	-	4	552
	AK030889.1	-	4	537
	AK088679.1	-	4	538
	AK135977.1	-	4	586
	AK146677.1	-	4	555
	AK152360.1	-	4	555
	AK159433.1	-	4	586
	AK165158.1	-	4	554
	AK166104.1	-	4	586
	AK167699.1	-	4	526
	AK169326.1	-	4	555
	BC012041.1	-	4	534	2648390
	X14206.1	-	4	559

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013063, U94340, BC085765.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
DNA repair
base-excision repair
double-strand break repair
transcription, DNA-templated
regulation of transcription, DNA-templated
protein ADP-ribosylation
cellular response to DNA damage stimulus
mitochondrion organization
transforming growth factor beta receptor signaling pathway
protein autoprocessing
signal transduction involved in regulation of gene expression
mitochondrial DNA metabolic process
cellular response to insulin stimulus
cellular response to oxidative stress
protein modification process
regulation of growth rate
DNA damage response, detection of DNA damage
mitochondrial DNA repair
positive regulation of transcription from RNA polymerase II promoter
behavioral response to cocaine
positive regulation of SMAD protein import into nucleus
protein poly-ADP-ribosylation
cellular response to superoxide
regulation of single strand break repair
positive regulation of transcription regulatory region DNA binding

Function(s)

DNA binding
chromatin binding
NAD+ ADP-ribosyltransferase activity
protein binding
transcription factor binding
zinc ion binding
transferase activity
transferase activity, transferring glycosyl groups
enzyme binding
protein kinase binding
identical protein binding
poly(A) RNA binding
metal ion binding
protein N-terminus binding
NAD binding
R-SMAD binding